"mso-bidi-font-style: normal">  It is unclear who these were from the Greek phrase alone, which simply means, “those from Him.” Yet by the context these were probably His family members; in other writings of that time the same word was used to describe one’s family.[xv]  They thought He must have gone crazy (literally, to stand outside of one’s self, thus be out of one’s mind)[xvi] because of how He had been acting, so they started out to “lay hold of Him”(take power over Him, implying by force).  The Amplified Bible clarifies it for us too: “And when those who belonged to Him (His kinsmen) heard it, they went out to take Him by force, for they kept saying, He is out of His mind (beside Himself, deranged)!” (Mark 3:21, amp)